Melatonin Use Linked to Increased Heart Failure Risk
Melatonin Use and Heart Failure Risk
A recent study presented at the American Heart Association’s 2025 Scientific Sessions reveals that long-term use of melatonin supplements, commonly taken for insomnia, is linked to a 90% increased risk of heart failure. Researchers found that adults using melatonin for a year or more were significantly more likely to be diagnosed with heart failure and experienced higher rates of hospitalization compared to non-users.
Understanding Melatonin’s Role
Melatonin is a natural hormone regulating the sleep-wake cycle, produced by the pineal gland. Synthetic melatonin supplements are widely available over the counter and often used to improve sleep quality. However, the unregulated nature of these supplements means potency and purity can vary, possibly contributing to adverse cardiovascular effects observed in long-term users.
Implications for Insomnia Treatment
This study’s findings highlight the need for caution when using melatonin chronically, especially among those with existing health concerns. Physicians and patients should consider alternative insomnia therapies and closely monitor heart health if melatonin use continues. Further research is essential to understand the mechanisms behind these risks fully.
About the Organizations Mentioned
American Heart Association
The **American Heart Association (AHA)** is the oldest and largest voluntary organization in the United States dedicated to fighting heart disease and stroke, two leading causes of death globally. Founded nearly 100 years ago, it has evolved into a relentless force focused on improving cardiovascular health and extending healthy life expectancy through research, advocacy, education, and community initiatives[3][6]. AHA’s mission is to be “a relentless force for a world of longer, healthier lives,” with a strategic 2030 Impact Goal to equitably increase healthy life expectancy in the U.S. from 66 to at least 68 years and worldwide from 64 to at least 67 years by 2030[1][5]. This ambitious vision guides its investments in cutting-edge research, quality improvement programs, and advocacy for policies that promote access to care, healthy environments, and health equity[1][4]. Key achievements include funding more cardiovascular research than any U.S. organization except the federal government—over $6 billion since 1949—and contributing to significant reductions in death rates from stroke (13.6%) and heart disease (15.1%) since 2018[3]. Through initiatives like Mission: Lifeline EMS, the AHA improves prehospital care for heart attacks and strokes, optimizing patient outcomes[8]. The organization also advances health equity by addressing social determinants of health and expanding care access across diverse and underserved populations, including rural and LGBTQ+ communities[2]. Its workforce is a collaborative mix of staff, volunteers, donors, and partners united by a shared purpose and cultural awareness[2]. Notable for its comprehensive policy advocacy, the AHA influences healthcare reform, community health, and maternal health policies based on scientific consensus, shaping health systems and public health at multiple levels[4]. Overall, the American Heart Association combines scientific rigor, community engagement, and policy influence to drive innovative solutions in cardiovascular health, making it vital for business and technology sectors interested in health innovation and impact.
