Antidepressants Ranked by Side Effects: Weight Changes and Personalized Monitoring
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First League Table of Antidepressant Side Effects
For the first time, a comprehensive ranking of antidepressants by their physical side effects has been published, shedding light on which medications may cause weight gain or loss. This study analyzed data from over 58,000 patients during the initial eight weeks of treatment, highlighting significant differences among 30 antidepressants.
Weight Change and Health Impacts
The research found that some antidepressants are associated with weight changes of up to 4 kg. For example, agomelatine users tended to lose weight, while others like maprotiline were linked to weight gain. Beyond weight, variations in heart rate and blood pressure were also observed, underscoring the importance of monitoring physical health during treatment.
Personalized Treatment and Monitoring
Experts emphasize the value of personalized medication choices and regular health check-ups to manage side effects effectively. Shared decision-making between patients and healthcare providers can help balance antidepressant benefits with potential physical impacts, ensuring safer and more tailored mental health care.