Forever Chemicals Accelerate Aging in Men Aged 50-65, Study Finds

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Men in their 50s may be aging faster due to toxic ‘forever chemicals’ - CNN

Men in Their 50s Facing Faster Aging from Forever Chemicals

Recent research reveals that toxic "forever chemicals" known as PFAS are accelerating aging in men aged 50 to 65 more than at other life stages. These persistent pollutants, found in everyday products like non-stick cookware and water-resistant fabrics, trigger epigenetic changes that speed up biological aging. A study analyzing blood samples from over 300 U.S. adults showed PFNA and PFOSA, present in 95% of participants, strongly predict faster cellular aging in this midlife group.[1][3]

Why Middle-Aged Men Are Most Vulnerable

Midlife marks a critical window for age-related issues like heart disease and metabolic disorders, amplifying PFAS impacts. Unlike younger men or those over 65, where links were weaker, middle-aged men exhibited pronounced effects, possibly worsened by lifestyle factors such as smoking. Women showed smaller, less consistent associations, highlighting sex-specific risks.[2][4]

Health Risks and Urgent Calls for Action

PFAS exposure raises cancer, cardiovascular disease, and immune risks, contaminating 45% of U.S. drinking water. With 5 out of 6 Americans urging stronger government protections, experts demand regulations on emerging PFAS alternatives to curb this hidden aging accelerator.[1][3]

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