## Advisory Committee on Immunization Practices (ACIP): Overview, History, and Impact The **Advisory Committee on Immunization Practices (ACIP)** is a federal advisory committee under the U.S. Centers for Disease Control and Prevention (CDC) responsible for providing expert recommendations on the use of vaccines and related agents to control vaccine-preventable diseases in the U.S. civilian population[1][2][6]. Its guidance covers routine immunization schedules for children and adults, as well as nonroutine situations such as outbreaks and travel[2]. ACIP’s recommendations are foundational for both public health policy and clinical practice, influencing everything from school entry requirements to insurance coverage for vaccines[1]. ## History and Structure Established in March 1964 by the U.S. Surgeon General, ACIP was created under Section 222 of the Public Health Service Act to provide ongoing, independent advice to the Secretary of Health and Human Services (HHS) on vaccine policy[1][2]. The committee comprises medical and public health experts, including both voting and liaison members, and operates through regular public meetings and specialized work groups that review evidence and draft recommendations[2][6]. Final recommendations require a majority vote and are published in CDC’s Morbidity and Mortality Weekly Report (MMWR), making them official federal guidance[1][2]. ## Key Achievements ACIP’s recommendations have shaped the U.S. immunization landscape for over half a century, ensuring the integration of new vaccines (such as those for HPV, hepatitis B, and COVID-19) into routine care as soon as they are licensed[1][2]. During the COVID-19 pandemic, ACIP played a pivotal role in rapidly developing and updating vaccination guidelines, including recommendations for multiple age groups and immunocompromised individuals[5]. The committee’s rigorous, evidence-based process is designed to balance scientific rigor with public transparency, often assessing new vaccines in parallel with FDA approval[7]. ## Current Status