Melatonin Linked to Higher Heart Failure Risk in Long-Term Use, New Study Finds

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Common Supplement Shows Concerning Link to Heart Failure - ScienceAlert

Introduction

A widely used supplement for sleep troubles is now under scientific scrutiny after new findings suggest a concerning link to heart failure. Melatonin, often taken to help with insomnia or jet lag, may carry risks for those using it long-term, according to a study presented at the American Heart Association’s 2025 Scientific Sessions.

Study Insights

Researchers analyzed health records of chronic insomnia patients and found those who used melatonin for a year or more had a higher risk of heart failure diagnosis, hospitalization, and death from any cause. The study focused on individuals with persistent sleep issues, making it unclear if occasional users face similar risks. Experts caution that chronic insomnia itself may contribute to poor heart health, complicating the results.

What This Means

While melatonin is available over the counter and generally considered safe for short-term use, these findings highlight the need for caution. Those with ongoing sleep problems should consult healthcare providers before long-term use. More research is needed to fully understand the connection between melatonin and cardiovascular outcomes.

About the Organizations Mentioned

American Heart Association

The **American Heart Association (AHA)** is the oldest and largest voluntary organization in the United States dedicated to fighting heart disease and stroke, two leading causes of death globally. Founded nearly 100 years ago, it has evolved into a relentless force focused on improving cardiovascular health and extending healthy life expectancy through research, advocacy, education, and community initiatives[3][6]. AHA’s mission is to be “a relentless force for a world of longer, healthier lives,” with a strategic 2030 Impact Goal to equitably increase healthy life expectancy in the U.S. from 66 to at least 68 years and worldwide from 64 to at least 67 years by 2030[1][5]. This ambitious vision guides its investments in cutting-edge research, quality improvement programs, and advocacy for policies that promote access to care, healthy environments, and health equity[1][4]. Key achievements include funding more cardiovascular research than any U.S. organization except the federal government—over $6 billion since 1949—and contributing to significant reductions in death rates from stroke (13.6%) and heart disease (15.1%) since 2018[3]. Through initiatives like Mission: Lifeline EMS, the AHA improves prehospital care for heart attacks and strokes, optimizing patient outcomes[8]. The organization also advances health equity by addressing social determinants of health and expanding care access across diverse and underserved populations, including rural and LGBTQ+ communities[2]. Its workforce is a collaborative mix of staff, volunteers, donors, and partners united by a shared purpose and cultural awareness[2]. Notable for its comprehensive policy advocacy, the AHA influences healthcare reform, community health, and maternal health policies based on scientific consensus, shaping health systems and public health at multiple levels[4]. Overall, the American Heart Association combines scientific rigor, community engagement, and policy influence to drive innovative solutions in cardiovascular health, making it vital for business and technology sectors interested in health innovation and impact.

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